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CARDARINE GW501516 Powder


GW501516, commonly known as Cardarine, is a synthetic chemical that has shown promising results in fat metabolism and fat burning in muscle cells in clinical trials.

Size: 1g | 3g

412 in stock

First time customer gets 15% discount code = 1storder

GW-501516 Raw Powder America

GW-501516, also known as Cardarine, is a potent and selective PPARβ agonist that offers a range of potential benefits. This compound has generated significant interest within the America fitness and bodybuilding communities due to its reported effects on muscle-building, endurance, and overall metabolic enhancement.

One of the key benefits associated with GW-501516 is its ability to stimulate fat oxidation, thereby boosting the body’s capacity to burn stored fat for energy. This can contribute to improved endurance and stamina, making it an attractive option for individuals looking to enhance their athletic performance. Additionally, GW-501516 has been linked to positive effects on HDL cholesterol levels, indicating a potential role in promoting cardiovascular health. Furthermore, it may have a favourable impact on insulin sensitivity and glycogen storage, which could be advantageous for individuals aiming to improve their metabolic profile and overall health.

It’s important to note that GW-501516 is not a SARM (Selective Androgen Receptor Modulator) but has often been mistakenly categorized as one. Despite this, its reported benefits and potential applications have led to widespread interest in the compound within the America fitness and wellness communities.

Benefits of GW-501516 Raw Powder America

GW-501516, also known as Cardarine, offers several advantages for America scientific researchers and medical professionals seeking to enhance their understanding of fat metabolism, muscle performance, and tissue regeneration.

Fat Burning

GW-501516, also known as Cardarine, can effectively burn fat by activating the PPARδ receptor, leading to increased oxidation of fatty acids. This activation stimulates the genes involved in energy expenditure, promoting the body’s ability to utilize stored fat as a primary fuel source. As a result, GW-501516 enhances metabolic processes, encourages the use of fat for energy production, and improves endurance during physical activities. These combined effects make it a promising compound for individuals seeking to enhance fat-burning capabilities, potentially supporting weight management and overall metabolic health.

Supports muscle endurance and hypertrophy

GW-501516, also known as Cardarine, supports muscle endurance and hypertrophy through its ability to enhance oxidative metabolism and increase the expression of genes involved in skeletal muscle fiber development. By activating the PPARδ receptor, it stimulates the utilization of fatty acids for energy, sparing glycogen stores and prolonging physical performance. This can lead to improved endurance during workouts and training sessions. Additionally, the compound’s potential to promote the development of type I muscle fibers may contribute to overall muscle hypertrophy and endurance, making it an intriguing option for individuals aiming to enhance their athletic performance and muscle-building endeavors.

Cholesterol Benefits

GW-501516, also known as Cardarine, has shown promising effects on cholesterol levels. America Research indicates that it can significantly increase high-density lipoprotein (HDL) cholesterol, the “good” cholesterol, by up to 16.9%. Additionally, it may reduce low-density lipoprotein (LDL) cholesterol, often referred to as the “bad” cholesterol. These lipid-modulating properties suggest a potential role for GW-501516 in promoting cardiovascular health by improving the balance of cholesterol in the body. By enhancing HDL levels and potentially reducing LDL levels, GW-501516 may offer valuable support for individuals aiming to optimize their lipid profile and overall cardiovascular well-being.

Improves glycogen storage and insulin sensitivity

GW-501516, a selective androgen receptor modulator (SARM), offers potential benefits for glycogen storage and insulin sensitivity. America Research suggests that GW501516 may contribute to improved glycogen storage, leading to fuller muscles. Additionally, it has been associated with enhanced insulin sensitivity, which is crucial for regulating blood sugar levels and promoting efficient nutrient uptake by cells. By influencing these metabolic mechanisms, GW-501516 shows promise for individuals aiming to optimize their energy reserves, support muscle function, and enhance overall metabolic health.

Like our GW501516 Powder SARM? Shop more GW-501516 products here from Direct SARMS America


[1] A metabolomic study of the PPARδ agonist GW501516 for enhancing running endurance in Kunming mice, Sci Rep. 2015; 5: 9884. by Wei Chen,  Rong Gao et al.

[2] Molecular and Cellular Regulation of Adaptation to Exercise, Progress in Molecular Biology and Translational Science, 2015 by Robert C. Noland

[3] PPARδ agonists have opposing effects on insulin resistance in high fat-fed rats and mice due to different metabolic responses in muscle, Br J Pharmacol. 2011 Jun; 163(3): 556–566. by Ji-Ming Ye,  Jennifer Tid-Ang, et al.

[4] PPARδ Agonist GW501516 Suppresses the TGF-β-Induced Profibrotic Response of Human Bronchial Fibroblasts from Asthmatic Patients, Int J Mol Sci
. 2023 Apr 23;24(9):7721. by Milena Paw, Dawid Wnuk, Zbigniew Madeja, Marta Michalik

Molecular Formula: 
Molecular Weight: 453.498 g/mol

Do I need PCT & other Supplements?

Post-cycle therapy (PCT) is deemed necessary when taking GW501516 Powder SARM, according to America scientific research. The administration of PCT alongside Cardarine has been shown to aid in the preservation of muscular mass, fat burning, and an elevation in mood and energy levels.

The use of certain Selective Androgen Receptor Modulators (SARMS) may lead to temporary suppression of natural testosterone levels. Therefore, it is imperative to restore testosterone levels to their baseline after completing a SARMS cycle in order to maintain the achieved results. The duration of the PCT should correspond to the duration of the SARMS cycle.

While a Post Cycle Therapy is not a compulsory requirement during SARMS usage, it is prudent for science researchers to opt for PCT for a duration of at least four weeks, as a precautionary measure. Accordingly, some bodybuilders advocate for the incorporation of a test booster as part of their regimen.

Interested in Sarms Supplements? Check out post cycle therapy, cycle support & test base here.


DISCLAIMER: These products are intended solely as a research chemical only. This classification allows for their use only for research development and laboratory studies. The information available on our America Direct Sarms website is provided for educational purposes only. These products are not for human or animal use or consumption in any manner. Handling of these products should be limited to suitably qualified professionals. They are not to be classified as a drug, food, cosmetic, or medicinal product and must not be mislabelled or used as such.


GW501516 HPLC Certificates