Buy DSIP (Delta Sleep-Inducing Peptide), a neuropeptide known for its potential to promote restful sleep, reduce stress, and regulate hormonal balance in the body.
Delta Sleep-Inducing Peptide (DSIP) is a naturally occurring neuropeptide, consisting of nine amino acids, that was first discovered in the early 1970s. Found within the brain and other tissues, this peptide plays a significant role in sleep cycle regulation.
It is known for its ability to induce delta wave sleep, the deepest and most restorative phase of the sleep cycle. Beyond its association with sleep efficiency, it has been studied for its potential to modulate stress, balance hormone levels, and influence pain perception.
Initially believed to act as a hypothalamic hormone, DSIP has a role that goes beyond regulating sleep patterns, showing similarities to the broad effects of growth hormone. Research suggests that DSIP may inhibit somatostatin, a protein that slows muscle growth, hinting at its wider potential uses.
Studies also indicate that DSIP could affect various systems in the body, including the endocrine and immune systems, with possible benefits like reducing oxidative stress, stabilizing blood pressure, and supporting mitochondrial function.
The peptide’s mechanisms of action mainly works by regulating physiological processes related to stress and sleep. It interacts with the hypothalamic-pituitary-adrenal (HPA) axis to help control the release of cortisol, a key stress hormone involved in the body’s stress response.
It also affects the central nervous system by increasing gamma-aminobutyric acid (GABA) levels, a neurotransmitter that reduces brain overactivity and promotes relaxation. This action is believed to play a major role in it’s ability to help induce and maintain restful sleep.
Additionally, it helps stabilize circadian rhythms, which are essential for maintaining a healthy sleep-wake cycle. While these effects are promising, further research is needed to fully understand how it interacts with the body at a molecular level.
Molecular Formula: C35H48N10O15
Molecular Weight: 848.824
Sequence: Trp-Ala Gly Gly AspAla-Ser-Gly-Glu
View our DSIP High-Performance Liquid Chromatography (HPLC) Certificate here.
Buy DSIP Epithalon Nasal Stack
Buy DSIP Epithalon Nasal Stack America for clinical research purposes from Direct Sarms, available in 15 ml and 30 ml bottles.
Epithalon is associated with activating telomerase and slowing the aging process. Together, these peptides may help with age-related decline, inflammation, recovery, and stress resilience. Early studies show promise, but more research is needed to confirm their safety and effectiveness.
Buy DSIP Pre-Mixed Pen
Buy DSIP pre-mixed pen America today, a convenient device for administering Delta Sleep-Inducing Peptide.
This ready-to-use pen eliminates manual mixing, ensuring precise dosing. Compact, portable, and easy to use, it’s perfect for researchers seeking simplicity and accuracy.
Buy DSIP Peptide Vial America for research use from Direct Sarms. Available as a lyophilized powder in 2 mg, 5 mg, and 10 mg vials. Before use, they need to be reconstituted with bacteriostatic water.
Can DSIP be combined with other peptides?
A 2024 study explored the sleep-enhancing effects of DSIP-CBBBP, a fusion peptide secreted by Pichia pastoris [12]. Using a PCPA-induced insomnia mouse model, researchers assessed its impact on neurotransmitters like 5-HT, glutamate, dopamine, and melatonin. Results show that DSIP-CBBBP effectively restores neurotransmitter balance and improves sleep more significantly than delta sleep peptide alone, highlighting its potential for sleep-related therapies.
Is DSIP safe?
Current America research is still in its early stages, and more studies are required to fully assess its safety and long-term effects.
Can DSIP be used for conditions other than sleep?
Some early research and anecdotal evidence suggest that it may also have benefits for reducing stress, supporting recovery from fatigue, and managing certain hormonal imbalances. However, these uses are not yet well-established and require further scientific validation.
Does DSIP have any side effects?
Like any substance with potential therapeutic applications, it may come with side effects, though research in this area is still limited. There have been some reports of mild adverse effects, such as headaches, dizziness, or nausea. It is also possible that prolonged use or incorrect dosages could result in unanticipated complications. Since it interacts with the body’s natural hormonal and neurological systems, individual responses may vary significantly.
Is DSIP legal?
The legal status differs globally. Some regions classify it as a research chemical, restricting its use to scientific studies, while others have minimal regulation or leave it unregulated but not approved for therapeutic use. The FDA does not approve it for medical purposes, and its sale outside of research settings may violate regulations. For those looking to buy DSIP, it’s essential to understand that local laws governing its purchase and use may apply, so conducting thorough research or seeking legal advice is highly recommended.
For more information, explore our latest blog posts dedicated to DSIP peptide.
Buy DSIP peptide America from Direct Sarms, a reliable source for research-grade peptides. It comes in 2 mg, 5 mg, and 10 mg lyophilized powder vials, 15 ml and 30 ml nasal sprays, and 5 mg pre-mixed pens. Produced to 99% purity, this peptide is perfect for laboratory use, ensuring accurate and dependable research results.
At Direct Sarms, we prioritize strict quality control to ensure our peptides are potent and reliable. With a focus on accuracy and consistency, we provide precise dosing and dependable results for all your research needs.
[1] D Schneider-Helmert (1981) Effects of delta-sleep-inducing peptide on 24-hour sleep-wake behaviour in severe chronic insomnia – European Neurology, 1987, Volume 27 (Issue 2), Pages 120-9.
[2] F Bes, W Hofman, J Schuur, and C Van Boxtel (1992) Effects of delta sleep-inducing peptide on sleep of chronic insomniac patients. A double-blind study – Neuropsychobiology, 1992, Volume 26 (Issue 4), Pages 193-7.
[3] D Schneider-Helmert, F Gnirss, M Monnier, J Schenker, and G A Schoenenberger (1981) Acute and delayed effects of DSIP (delta sleep-inducing peptide) on human sleep behavior – International Journal of Clinical Pharmacology, Therapy & Toxicology, 1981 Aug, Volume 19 (Issue 8), Pages 341-5.
[4] W Larbig, W D Gerber, M Kluck, and G A Schoenenberger (1984) Therapeutic effects of delta-sleep-inducing peptide (DSIP) in patients with chronic, pronounced pain episodes. A clinical pilot study – European Neurology, 1984, Volume 23 (Issue 5), Pages 372-85.
[5] A Nakamura, M Nakashima, T Sugao, H Kanemoto, et al (1988) Potent antinociceptive effect of centrally administered delta-sleep-inducing peptide (DSIP) – European Journal Pharmacology, 1988 Oct 18, Volume 155 (Issue 3), Pages 247-53.
[6] Elena M. Khvatova, Natalia A. Rubanova, Igor A. Prudchenko, and Inessa I. Mikhaleva (1995) Effects of delta-sleep inducing peptide (DSIP) and some analogues on the activity of monoamine oxidase type A in rat brain under hypoxia stress – FEBS Letters, Volume 368, Issue 2, 17 July 1995, Pages 367-369.
[7] L H Lindström, R Ekman, H Walleus, and E Widerlöv (1985) Delta-sleep inducing peptide in cerebrospinal fluid from schizophrenics, depressives and healthy volunteers – Progress in Neuropsychopharmacology & Biological Psychiatry, 1985, Volume 9 (Issue 1), Pages 83-90.
[8] Åsa Westrin, Rolf Ekman, and Lil Träskman-Bendz (1998) High delta sleep-inducing peptide-like immunoreactivity in plasma in suicidal patients with major depressive disorder – Biological Psychiatry, Volume 43, Issue 10, 15 May 1998, Pages 734-739.
[9] Elena M Khvatova, Victor N Samartzev, Pavel P Zagoskin, Igor A Prudchenko, and Inessa I Mikhaleva (2003) Delta sleep inducing peptide (DSIP): effect on respiration activity in rat brain mitochondria and stress protective potency under experimental hypoxia – Peptides, 2003 Feb, Volume 24 (Issue 2), Pages 307-11.
[10] M Backmund, K Meyer, H B Rothenhaeusler, and M Soyka (1998) Opioid detoxification with delta sleep-inducing peptide: results of an open clinical trial – Journal of Clinical Psychopharmacology, 1998 Jun, Volume 18 (Issue 3), Pages 257-8.
[11] P Dick, C Costa, K Fayolle, M E Grandjean, A Khoshbeen, and R Tissot (1984) DSIP in the treatment of withdrawal syndromes from alcohol and opiates – European Neurology, 1984, Volume 23 (Issue 5), Pages 364-71.
[12] Xiaoxiao Mu, Lijun Qu, Liquan Yin, Libo Wang, et al (2024) Pichia pastoris secreted peptides crossing the blood-brain barrier and DSIP fusion peptide efficacy in PCPA-induced insomnia mouse models – Frontiers in Pharmacology,
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